Robert D. Levy

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Vision Statement

Dr.

Robert D. Levy

Position

Professor

Division

Respiratory

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Overview
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Research Interests

Dr. Levy’s major research interests are related to physiologic and functional outcomes following lung transplantation. He has additional interests related to chronic disease management and global health in resource-challenged settings.

Research Summary

Research Highlights

Personal

Dr. Levy trained in Internal and Respiratory Medicine at McGill University in Montreal, Quebec, Canada and was a Research Director at the Meakins-Christie Laboratories. He is currently a Professor of Medicine at the University of British Columbia in Vancouver. He is former Director of the Respiratory Division at St. Paul’s Hospital in Vancouver, BC and Past-President of the Canadian Thoracic Society.

Dr. Levy is the Medical Director of the British Columbia Lung Transplant Program and Associate Director of the Pulmonary Hypertension Program at Vancouver General Hospital. He is the Medical Director for the Vancouver Coastal Health Regional Medicine Program. He is also the Specialist Lead for the Providence Health Care Chronic Disease Management Strategy.

Education and Affiliations
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Education

M.D.,C.M McGill University, Montreal, Quebec,

FRCPC Royal Victoria Hospital, Montreal, Quebec Resident, Internal Medicine,

FRCPC Respiratory Training Program, McGill University Subspecialty Resident, Respiratory Medicine,

Affiliations

Publications and Awards
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Recent Publications

  • Yang D, Wilson JM, Bai C, Yee J, Wilcox PG, Khalil N, Levy RD. Acute exacerbation of pulmonary fibrosis following single lung transplantation. In press, Can Respir J April 2011.
  • Chin MW, Levy RD, Yoshida EM, Byrne MF. Sitaxsentan-induced acute severe hepatitis treated with glucocorticoid therapy. In press, Can Respir J May 2011.
  • Petrovic V, Ryerson CJ, Levy RD. Long-term survival in idiopathic pulmonary arterial hypertension associated with massive pulmonary artery dilatation. In press June 2010, Can Respir J.
  • Borrie AE, Ostrow DN, Levy RD, Swiston JR. Assessing response to therapy in idiopathic pulmonary arterial hypertension: A consensus survey of Canadian pulmonary hypertension physicians.  In press Sept 2010, Can Respir J.
  • Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly J, Agusti A, Calverley PMA, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EFM, Scholand MB, Coon H, Hoidal J, Silverman EK. Multi-study fine mapping of chromosome 2q identifies XRCC5 as a COPD susceptibility gene. Am J Respir Crit Care Med. 2010;182:605-13. Epub 2010 May 12.
  • Marshall GB, Silva CI, English JC, Levy RD, Muller NL. Misplaced pulmonary arteries in an adult patient with pulmonary hypertension. Brit J Radiol 2010; 83: e5-9.
  • Mehta S, Helmersen D, Provencher S, Hirani N, Rubens FD, de Perrot M, Blostein M, Boutet K, Chandy G,  Dennie C, Granton J, Hernandez P, Hirsch AM, Laframboise K, Levy RD, Lien D, Martel S, Shoemaker G, Swiston J, Weinkauf J. Diagnostic evaluation and management of chronic thromboembolic pulmonary hypertension (CTEPH): A clinical practice guideline. Can Respir J 2010; 17; 301-334.
  • Park K, Ostrow DN, Levy RD, Swiston J. Transition from intravenous epoprostenol to oral or subcutaneous therapy in pulmonary arterial hypertension: A case series and systematic review. Can Respir J 2010; 18: 157-162.
  • Bakke PS, Zhu G, Gulsvik A, Agusti AGN, Calverley PMA, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EFM, Lomas D, Silverman EK, Pillai SG. Candidate genes for chronic obstructive pulmonary disease in two large data sets. Eur Respir J. 2010 Jul 7. [Epub ahead of print].
  • Quon BS, Reid JD, Wong P, Wilcox PG, Javer A, Wilson JM, Levy RD. Burkholderia gladioli – a predictor of poor outcome in cystic fibrosis patients who receive lung transplants? In press, Can Respir J Oct 2010.
  • Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Augustí AGN, Calverley PMA, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EFM, Paré PD, Levy RD, Coxson HO, Lomas DA, Hersh CP, Silverman EK. Alpha-1 antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts.  Chest. 2010 Nov;138(5):1125-32. Epub 2010 Jul 1.
  • Bahadori K, FitzGerald JM, Levy RD, Fera T, Swiston J. Risk factors and outcomes associated with chronic obstructive pulmonary disease exacerbations requiring hospitalization. Can Resp J 2009;16: e43-e49.
  • Camp PG, Coxson HO, Levy RD, Pillai S, Anderson W, Vestbo J, Kennedy S, Silverman EK, Lomas DA, Paré PD. Sex differences in emphysema and airway disease in smokers. Chest 2009 136:1480-1488.
  • Levy AR, Sobolev BG, James D, Barrable W, Clarke-Richardson P, Sullivan SD, Keown P, Chung S, Straatman L, Levy RD.  The costs of change: direct medical costs of solid organ transplantation in British Columbia, Canada, 1995-2003.  Value in Health. 2009; 12: 282-292.
  • Zhu G, Agusti A, Gulsvik A, Bakke P, ICGN investigators (includes Levy RD), Coxson H, Lomas DA,  Silverman EK, Pillai SG. CTLA4 gene polymorphisms are associated with chronic bronchitis. Eur Resp J 2009; 34: 598 – 604.
  • Zhu G, ICGN investigators (includes Levy RD), Gulsvik A, Bakke P, Ghatta S, Anderson W, Lomas DA, Silverman EK, Pillai SG. Association of TRPV4 Gene Polymorphisms with Chronic Obstructive Pulmonary Disease. Hum Mol Genet 2009; 18: 2053 – 2062.
  • Camp PG, Chaudhry M, Platt H, Roch M, Road J, Sin D, Levy RD. The sex factor: epidemiology and management of COPD in British Columbia. Can Respir J 2008; 15: 417-422.
  • Camp PG, Levy RD. A snapshot of chronic obstructive pulmonary disease in British Columbia and Canada.  BC Medical Journal 2008; 50: 80-84.
  • Dodd JD, DeJong PA, Levy RD, Coxson HO, Mayo JR. Conventional high-resolution CT versus contiguous multidetector CT in the detection of bronchiolitis obliterans syndrome in lung transplant. J Thoracic Imaging. 2008; 23: 235-243.
  • Lomas DA, Silverman EK, Edwards LD, Miller BE, Coxson HO, Tal-Singer R, on behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators (includes Levy RD). Evaluation of serum CC-16 as a biomarker for chronic obstructive pulmonary disease in the ECLIPSE cohort. Thorax 2008; 63: 1058 – 63.
  • Maltais F, Bourbeau J, Shapiro S, Lacasse Y, Perrault H, Baltzan M, Hernandez P, Rouleau M, Julien M, Parenteau S, Paradis B, Levy RD, Camp P, Lecours R, Audet R, Hutton B, Penrod JR, Picard D, Bernard S. Effects of home-based pulmonary rehabilitaion in patients with chronic obstructive pulmonary disease: a randomized trial. Ann Int Med 2008; 149: 869-878.
  • Mathur S, Levy RD, Reid WD. Skeletal muscle strength and endurance in recipients of lung transplants. Cardiopul Phys Therapy J 2008; 19: 84-93.
  • Patel BD, Coxson HO, Pillai S, Agusti AGN, Calverley PMA, Donner CF, Make BJ, Müller NL, Rennard SI,  Vestbo J, Wouters EFM, Hiorns MP, Nakano Y, Camp P, Nasute-Fauerbach PV, Screaton NJ, Anderson WH,  Paré PD, Levy RD, Lake S, Silverman EK, Lomas DA. Airway Wall Thickening and Emphysema Show Independent Familial Aggregation in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2008; 178: 500-505.
  • Ting LSL, Partovi N, Levy RD, Ignaszewski AP, Ensom MHH. Performance of limited sampling strategies for predicting mycophenolate area under the curve in thoracic transplant recipients. J Heart Lung Transplant 2008; 27: 325-8.
  • Ting LSL, Partovi N, Levy RD, Riggs KW, Ensom MHH. Pharmacokinetics of mycophenolic acid and its phenol-glucuronide and acyl-glucuronide metabolites in stable thoracic transplant recipients. Ther Drug Monit 2008; 30: 282-291.
  • Kim WD, Ling SH, Coxson HO, English JC, Levy RD, Pare PD, Hogg JC. The association between small airway disease and emphysema phenotypes in chronic obstructive pulmonary disease. Chest 2007; 131: 1372-1378.
  • Ksienski D, Malhotra S, Walker B, Levy RD. Chest pain and cough in a 33-year-old postpartum woman. Chest 2007; 132:1389-92.
  • Mathur S, MacIntyre DL, Forster BB, Road JD, Levy RD, Reid WD. Preservation of eccentric torque of the knee extensors and flexors in people with COPD. J Cardiopulmonary Rehab 2007; 27: 411-416.
  • Zhu G, Warren L, Aponte J, Gulsvik A, Bakke P, Agusti A, Calverley PMA, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EFM, Anderson WH, Lomas DA, Silverman EK, Pillai SG. Polymorphisms in SERPINE2 are Associated with Chronic Obstructive Pulmonary Disease in Two Large Populations. Am J Respir Crit Care Med. 2007 Am J Respir Crit Care Med 176: 167-173.
  • de Jong PA, Dodd JD, Coxson HO, Storness-Bliss C, Paré PD, Mayo JR, Levy RD. Bronchiolitis obliterans following lung transplantation: early detection using CT. Thorax 2006;61:799-804.
  • Silva CIS, Flint JD, Levy RD, Müller NL. Diffuse lung cysts in lymphoid interstitial pneumonia: High-resolution CT and pathologic findings. J Thoracic Imaging 2006;21:241-244.
  • Ting LSL, Partovi N, Levy RD, Riggs KW, Ensom MHH. Limited sampling strategy for predicting mycophenolic acid area-under-the-curve in adult lung transplant recipients. Pharmacotherapy 2006; 26:1232-1240.
  • Ting LSL. Partovi N, Levy RD, Riggs KW, Ensom MHH. Pharmacokinetics of mycophenolic acid and its glucuronidated metabolites in stable lung transplant recipients. Ann Pharmacother 2006; 40:1509-1516.

Awards & Recognition

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Teaching/Students
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