David Moore

Address

Vision Statement

I conduct observational studies related to HIV prevention and treatment in order to understand how the efficacy evidence-based interventions translate into the real-world of HIV programming.

Dr.

David Moore

Position

Associate Professor

Division

Social Medicine

Phone

Email

Overview
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Research Interests

HIV prevention and control, HIV among men who have sex with men, HIV in sub-Saharan Africa; epidemiology; public health

Research Summary

My program of research encompasses the following two broad themes: 1) Health service research in to maximize the treatment and prevention benefits at a population level in British Columbia and in sub-Saharan Africa and 2) understanding the structural and socio-behaviour risks for HIV infection among men who have sex with men (MSM) in British Columbia. My program of research aims to provide policy makers in Canada and globally with critical information on how the design of HIV-related health services may affect the future shape of HIV epidemics.

Research Highlights

Personal

My wife and I support a Kenyan organization which provides a home for orphaned children in Busia, Kenya. For more information see: www.kenyanorphans.org

Education and Affiliations
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Education

MDCM, MHSc, FRCP(C),

Affiliations

,

Publications and Awards
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Recent Publications

1. Ng B, Moore D, Michelow W, Hogg,RS, Gustafson R, Trussler T, Robert W, Kanters S, Thumath M, McGuire M, Gilbert M, and the ManCount Study Team. Relationship between disclosure of same sex sexual activity to providers, HIV diagnosis and sexual health services for men who have sex with men (MSM) in Vancouver, Canada. 2014 Can J Pub Health 105 (3): 186 – 191.

2. Muldoon, KA, Duff P, Birungi J, Ngolobe M, Min J, King R, Nyonyintono M, Chen Y, Shannon K, Khanawka S, Moore D. Decisions, Decisions: The importance of egalitarian style decision-making on condom use among HIV sero-discordant couples in Uganda. 2014 Sex Trans Infect Aug;90(5):408-12. PMID: 24695989

3. Montaner JSG, Lima VD, Harrigan PR, Lourenço L, Yip B, Nosyk B, Wood E, Kerr T, Shannon K, Moore D, Hogg RS, Barrios R, Gilbert M, Krajden M, Gustafson R, Daly P, Kendall P. Expansion of HAART coverage is associated with sustained decreases in HIV/AIDS morbidity, mortality and HIV transmission – The “HIV Treatment as Prevention” experience in a Canadian setting. PloS One 2014;9(2): e87872. doi: 10.1371/journal.pone.0087872. PMID: 24533061

4. Forrest J, Stevenson B, Rich A, Michelow W, Pai J, Jollimore J, Raymond Fisher H, Moore D, Hogg RS, Roth EA. Community mapping and respondent-driven sampling of gay and bisexual men’s communities in Vancouver, Canada 2014 Cult Health Sex. 16 (3): 288 – 301. Feb 10. [Epub ahead of print] PMID: 24512070

5. Haley L, Wong J, Moore D, Chan K, Michelow W, Dawar M, Robert W, Hogg RS, Gilbert M and the ManCount Study Team. Prevalence and correlates of cigarette smoking among men who have sex with men (MSM) in Vancouver, Canada: A cross-sectional survey. 2014. J Behav Health 3(1): 1-8

6. Maung Maung T, Chen, B, Moore D, Chan K, Kanters, S, Michelow W, Hogg RS, Nakamura N, Robert W, Gustafson, R, Gilbert M and the ManCount Study Team Risks for HIV and other sexually transmitted infections among Asian men who have sex with men in Vancouver, British Columbia: A cross-sectional survey BMC Public Health 2013 Aug 16;13(1):763. PMID: 23947623

7. Ekwaru JP, Campbell J, Malamba S, Moore DM, Were W, Mermin J. The effect of opportunistic illness on HIV RNA viral load and CD4+ T cell count among HIV-positive adults taking antiretroviral therapy. J Int AIDS Soc. 2013 Apr ;16:1 – 6; 17355..PMID:23547778

8. Campbell J, Moore D, Degerman R, Kaharuza F, Were W, Muramuzi E, Odongo G, Wetaka M, Mermin J, Tappero JT. HIV-infected Ugandan adults taking ART with CD4 counts > 200 cells/µL who discontinue cotrimoxazole prophylaxis have increased risk of malaria and diarrhea. 2012 Clini Inf Dis Apr;54(8):1204-11. PMID 22423133

9. Muldoon KA, Birungi J, Berry N, Ngolobe M, Mwesigwa R, Shannon K, Moore DM. Supporting Southern-Led Research: Implications for North-South Research Partnerships. Can J Public Health. 2012 Mar-Apr;103(2):128-31.PMID: 22530536

10. Moore DM, Kanters S, Michelow W,, Gustafson R, Hogg RS, Kwag M, Trussler T, McGuire M, Robert W, Gilbert M and the ManCount Study Team. Implications for HIV prevention programs from a serobehavioural survey of who have sex with men in Vancouver, British Columbia: The ManCount Study. 2012 Can J Pub Health. Mar-Apr;103(2):142-6. PMID: 22530539

11. Mtambo A, Chan K, Shen A, Lima V, Hogg RS, Montaner JSG, Moore DM. Treatment limitations imposed by antiretroviral drug resistance mutations: a comparison of initial regimens containing boosted-PIs with those containing NNRTIs. HIV Medicine 2012 Mar;13(3):141-7. doi: 10.1111/j.1468-1293.2011.00950.x. PMID:22107262

12. Asiimwe F, Moore DM, Nakityo R, Were W, Campbell J, Barasa A, Mermin J, Kaharuza F. Clinical outcomes of HIV-infected patients with Kaposi’s sarcoma receiving non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in Uganda. HIV Medicine 2012 Mar;13(3):166-71. doi: 10.1111/j.1468-1293.2011.00955.x PMID: 22112164

Awards & Recognition

  • 14th Canadian Conference on HIV/AIDS Research. Vancouver, Canada. 2005. New Investigator Award – Clinical Track.
  • Canadian Institutes for Health Research – New Investigator Salary Support Award 2008 – 2013
  • 2009 – US Centers for Disease Control and Prevention – Nomination for Charles C. Shepard Science Award as a co-author for “Mortality in HIV-infected Ugandan Adults Receiving ART and Survival of Their HIV-Infected Children.”
Grants
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Grants

Role: Co-Principal Investigator (Eric Roth – PI)

Funding source: Canadian Institutes for Health Research

Title: Using the concept of positive deviance to identify harm reduction strategies associated with group sex events among gay and bisexual men in Vancouver’s Momentum Health Study

Period: 2014 – 2016

Annual budget: $CAN 67,484

Role: Principal Investigator

Funding source: St. Paul’s Hospital Department of Family and Community Medicine

Title: Physician knowledge, attitudes and prescribing behaviour regarding HIV testing, care and treatment: a pilot survey

Period: 2013 – 2014

Annual budget: $CAN 5000

Role: Principal Investigator

Funding source: Canadian Institutes for Health Research

Title: Predicting long-term success on antiretroviral therapy among individuals failing first-line treatment in Uganda

Period: 2012 – 2017

Annual budget: $CAN 169,165

Role: Co- Investigator (Hogg, RS – PI)

Funding source: Canadian Institutes for Health Research

Title: Determinants of late initiation and treatment interruption in a context of the

expansion highly active antiretroviral therapy (HAART) in British Columbia, Canada

Period: 2012 – 2014

Annual budget: $CAN 139,431

Role: Principal Investigator

Funding source: Canadian Institutes for Health Research

Title: ART program design and effect on clinical outcomes in rural Uganda: Secondary data analyses from the Home Based AIDS Care project;

Period: 2011 – 2014

Annual budget: $CAN 109,000

Role: co-Investigator (Hogg – PI)

Funding source: National Institutes of Health/ National Institute of Drug Abuse

Title: HAART optimism, drug use and risky sexual behavior and among men who have sex with men in British Columbia, Canada

Period: 2011 – 2016

Annual budget: $US 444,118

Role: co-Principal Investigator

Funding source: Canadian Institutes for Health Research

Title: Effect of ART expansion on community levels of viral load and HIV risk behaviour among men who have sex with men in British Columbia, Canada

Period: 2010 – 2015

Annual budget: $CAN 159,053

Role: co-Principal Investigator

Funding source: Global Health Research Initiative

Title: Canada-Africa Prevention Trials (CAPT) Network Proposal to Build African Capacity for HI/AIDS Prevention Trials

Period: 2010 – 2014

Annual budget: $CAN 450,000

Teaching/Students
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I supervise Ph.D., MSc and MPH students from the School of Population and Public Health at UBC and supervise rotations in Public Health HIV by medical students and Public Health and Preventive Medicine Residents from UBC and other medical schools.